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Updated: Nov 1, 2025

Sleeve Gastrectomy in Mice using Surgical Clips
Published on: November 14, 2020
Metabolic Surgery Outcomes in U.S. Patients with Class I Obesity
Dustin Baldwin1, Lisa Sanchez-Johnsen2, Roberto Bustos1
1Department of Surgery, Division of General, Minimally Invasive and Robotics, University of Illinois at Chicago, Chicago, Illinois, USA.
Abstract:
Although numerous studies outside the United States (U.S.) have explored weight loss and comorbidity resolution among patients with class I obesity (body mass index [BMI] 30-34.9 kg/m2) after metabolic surgery, few U.S.-based studies have been conducted. Our aim was to compare weight loss and comorbidity resolution among U.S. patients with class I obesity, who underwent laparoscopic sleeve gastrectomy (LSG) versus Roux-en-Y gastric bypass (RYGB). Weight loss and comorbidity data among only patients with class I obesity, who underwent LSG or RYGB, were examined. Between April 2009 and April 2017, 1215 metabolic surgeries were performed with 30 patients meeting the inclusion criteria (17 LSG and 13 RYGB). Percent total weight loss (%TWL) for LSG peaked at 12 months (20.85%), while RYGB %TWL peaked at 18 months (21.65%). Percent excess weight loss (%EWL) peaked at 12 months after LSG (83.59%) and 18 months after RYGB (98.29%). Overall follow-up was 56.3%, 36.7%, and 43.3% at 12, 18, and 24 months. LSG and RYGB were both successful with regard to resolution of medical comorbidities at 12 months. RYGB and LSG appear to have similar, successful outcomes among U.S. patients with class I obesity for weight loss and comorbidity resolution.
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