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Managing screening-detected subsolid nodules-the Asian perspective
Masaaki Sato1, Shun-Mao Yang1,2, Dong Tian1,3,4
1Department of Thoracic Surgery, University of Tokyo Hospital, Tokyo, Japan.
Translational Lung Cancer Research
|June 24, 2021
Summary
This review addresses challenges in managing subsolid pulmonary nodules, often detected via low-dose computed tomography (CT) screening. It provides insights for clinicians on handling these ground glass nodules (GGNs) in Asia.
Area of Science:
- Pulmonology
- Thoracic Surgery
- Radiology
Background:
- Low-dose computed tomography (CT) screening detects numerous small pulmonary nodules.
- Subsolid nodules, particularly ground glass nodules (GGNs), are frequently identified in Asia, often as lung adenocarcinomas or premalignant lesions, especially in female non-smokers.
Purpose of the Study:
- To discuss controversial issues and clinical conditions related to subsolid pulmonary nodules encountered in Asian practice.
- To present current evidence and expert opinions on managing GGNs, addressing guideline deficiencies.
Main Methods:
- Review article synthesizing existing evidence and expert opinions.
- Discussion of key management aspects including preoperative assessment, localization, surgical techniques, and non-surgical options.
Main Results:
- Identified significant challenges in managing subsolid pulmonary nodules due to a lack of comprehensive guidelines.
- Highlighted controversies in preoperative diagnosis, surgical approach, and treatment modalities for GGNs.
Conclusions:
- Subsolid pulmonary nodules present complex management dilemmas, particularly in the Asian context.
- The review aims to aid clinicians in making balanced decisions for GGN management and stimulate further guideline development.

