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Managing screening-detected subsolid nodules-the Asian perspective.

Masaaki Sato1, Shun-Mao Yang1,2, Dong Tian1,3,4

  • 1Department of Thoracic Surgery, University of Tokyo Hospital, Tokyo, Japan.

Translational Lung Cancer Research
|June 24, 2021
PubMed
Summary
This summary is machine-generated.

This review addresses challenges in managing subsolid pulmonary nodules, often detected via low-dose computed tomography (CT) screening. It provides insights for clinicians on handling these ground glass nodules (GGNs) in Asia.

Keywords:
Lung cancer screeninglocalizationsublobar resectionsubsolid nodules

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Area of Science:

  • Pulmonology
  • Thoracic Surgery
  • Radiology

Background:

  • Low-dose computed tomography (CT) screening detects numerous small pulmonary nodules.
  • Subsolid nodules, particularly ground glass nodules (GGNs), are frequently identified in Asia, often as lung adenocarcinomas or premalignant lesions, especially in female non-smokers.

Purpose of the Study:

  • To discuss controversial issues and clinical conditions related to subsolid pulmonary nodules encountered in Asian practice.
  • To present current evidence and expert opinions on managing GGNs, addressing guideline deficiencies.

Main Methods:

  • Review article synthesizing existing evidence and expert opinions.
  • Discussion of key management aspects including preoperative assessment, localization, surgical techniques, and non-surgical options.

Main Results:

  • Identified significant challenges in managing subsolid pulmonary nodules due to a lack of comprehensive guidelines.
  • Highlighted controversies in preoperative diagnosis, surgical approach, and treatment modalities for GGNs.

Conclusions:

  • Subsolid pulmonary nodules present complex management dilemmas, particularly in the Asian context.
  • The review aims to aid clinicians in making balanced decisions for GGN management and stimulate further guideline development.