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Scepter-Mini Balloon Assisted Coil Embolization of an Intracranial Arterial Aneurysm in a Child with PHACE Syndrome
Bharathi Dasan Jagadeesan1, Coridon Quinn Iv1, Kamran Masood1
1Depatment of Radiology, Neurosurgery and Neurology, University of Minnesota, Minneapolis, MN, USA.
Insights
This study details the successful treatment of a complex brain aneurysm in a child with PHACE syndrome using balloon-assisted coiling. The innovative technique navigated a narrow artery via a persistent trigeminal artery for effective aneurysm repair.
Area of Science:
- Pediatric Neurology
- Interventional Neuroradiology
- Vascular Malformations
Background:
- PHACE syndrome is a complex disorder associated with cerebrovascular abnormalities, including moyamoya arteriopathy and intracranial aneurysms.
- Cerebral vascular malformations are a significant feature in children diagnosed with PHACE syndrome.
- Aberrant intracranial arteries can complicate treatment of aneurysms in affected children.
Observation:
- A pediatric patient with PHACE syndrome presented with a growing left posterior-communicating artery aneurysm.
- The aneurysm originated from an aberrant left internal carotid artery (LICA) with a narrow proximal caliber.
- Standard endovascular approaches were challenging due to the LICA's anatomy.
Findings:
- Successful treatment of the LICA aneurysm was achieved using balloon-assisted coiling (BAC).
- A novel endovascular route was employed, navigating a microcatheter from the basilar artery into the LICA via a persistent trigeminal artery.
- A Scepter Mini balloon microcatheter facilitated aneurysm neck remodeling during the coiling procedure.
Implications:
- This case demonstrates a viable endovascular strategy for treating complex aneurysms in pediatric PHACE syndrome patients with challenging LICA anatomy.
- The successful use of a persistent trigeminal artery as an access route highlights its potential in complex neurovascular interventions.
- This approach may offer a less invasive alternative for managing specific cerebrovascular malformations in pediatric patients.
Abstract:
Cerebral vascular malformations constitute one of the key abnormalities in children with PHACE syndrome, which is characterized by Plaque like cutaneous hemangiomas, Posterior fossa abnormalities, arterial Cerebrovascular and Eye abnormalities, with or without Sternal clefts (PHACES when sternal clefts are present), and associated midline anomalies. Both moyamoya arteriopathy and intracranial aneurysms have been reported in children with this syndrome. Herein, we report the successful treatment of a growing left posterior-communicating artery aneurysm arising from an aberrant left internal carotid artery (LICA) with balloon assisted coiling (BAC) in a child with PHACE syndrome. We circumvented the limitations posed by the narrow caliber of the proximal LICA, by successfully navigating a coiling microcatheter from the basilar artery into the LICA via a persistent trigeminal artery. BAC was then achieved using a Scepter Mini balloon microcatheter for aneurysm neck remodelling.

