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Automatic detection of synaptic partners in a whole-brain Drosophila electron microscopy data set
Julia Buhmann1,2, Arlo Sheridan1, Caroline Malin-Mayor1
1HHMI Janelia Research Campus, Ashburn, VA, USA.
Nature Methods
|June 25, 2021
Abstract
None:
We develop an automatic method for synaptic partner identification in insect brains and use it to predict synaptic partners in a whole-brain electron microscopy dataset of the fruit fly. The predictions can be used to infer a connectivity graph with high accuracy, thus allowing fast identification of neural pathways. To facilitate circuit reconstruction using our results, we develop CIRCUITMAP, a user interface add-on for the circuit annotation tool CATMAID.

