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Deciphering the Role of Fluctuation Dependent Intercellular Communication in Neural Stem Cell Development

Amitava Giri1, Dola Sengupta2, Sandip Kar1

  • 1Department of Chemistry, IIT Bombay, Powai, Mumbai 400076, India.

ACS Chemical Neuroscience
|June 25, 2021
PubMed
Summary

Neural stem cells (NPCs) use intercellular communication for cell fate decisions. Transcriptional variability from cell cycles significantly impacts the neuron to NPC ratio during development, offering therapeutic insights.

Keywords:
Neural stem cellscell−cell communicationextrinsic fluctuationoscillationsignaling pathwaystochastic modeling

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