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Genomics02:02

Genomics

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Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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Genetic Screens02:46

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Human Genetics01:28

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Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
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Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
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Making a case for genomics in chiropractic education.

Kara D Burnham1, Leslie A K Takaki2

  • 1Kara Burnham is an associate professor at the University of Western States (8000 NE Tillamook Street, Portland, OR 97213; kburnham@uws.edu).

The Journal of Chiropractic Education
|June 25, 2021
PubMed
Summary
This summary is machine-generated.

Chiropractors increasingly encounter patient questions about direct-to-consumer genetic testing. An introductory clinical genomics course is essential for chiropractors to effectively address patient genomics inquiries and integrate this knowledge into primary care.

Keywords:
ChiropracticEducationGenomicsTeaching

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Area of Science:

  • Health Sciences
  • Genetics
  • Primary Care

Background:

  • Genomics is rapidly advancing and impacting healthcare.
  • The role of chiropractors in primary care necessitates understanding of genomic applications.
  • Patient interest in direct-to-consumer genetic testing is rising.

Purpose of the Study:

  • To assess chiropractors' current knowledge and utilization of genomics in patient care.
  • To determine the need for revising genetics education to include clinical genomics.
  • To evaluate the importance chiropractors place on genomics education.

Main Methods:

  • A survey of 181 chiropractors was conducted.
  • The survey included closed-ended and open-ended questions on genomics knowledge and practice.
  • Pearson correlation and content analysis were used for data evaluation.

Main Results:

  • 42% of chiropractors are consulted by patients 1-3 times monthly regarding genetic testing results.
  • Chiropractors' knowledge of genomics varies significantly.
  • 51% of chiropractors believe genomics education is moderately to extremely important.

Conclusions:

  • An introductory clinical genomics course is recommended for chiropractic education.
  • Enhanced training is needed to prepare chiropractors for patient genomics discussions.
  • Genomics education is crucial for chiropractors to effectively manage patient care.