Related Experiment Video
Updated: Nov 1, 2025

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
Published on: March 21, 2013
Severe acute orthostatic headache: spontaneous intracranial hypotension (SIH)
Pushpendra Nath Renjen1, Dinesh Mohan Chaudhari2, Nidhi Goyal3
1Neurology, Indraprastha Apollo Hospital, New Delhi, Delhi, India pnrenjen@hotmail.com.
Abstract:
The most common cause of spontaneous intracranial hypotension headache is a cerebrospinal fluid (CSF) leakage, but the underlying mechanisms remain unknown. Intracranial hypotension is characterised by diffuse pachymeningeal enhancement on cranial MRI features, low CSF pressure and orthostatic headaches mostly caused by the dural puncture. We report a 31-year-old woman who presented to our services with reports of continuous severe bifrontal headache, which increased on sitting up and resolved on lying down. MRI of the cervical and lumbosacral spine showed signs of CSF leak; hence, patient was diagnosed with spontaneous intracranial hypotension headache. A CT-guided epidural blood patch was done at L4-5 with fibrin glue injected at the site of leak. The patient's signs and symptoms improved after the procedure.
Related Concept Videos
Alterations in Blood Pressure
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
Equilibrium and Balance
Hypertension I: Introduction
Hypertension III: Clinical Manifestations and Diagnostic Studies
Disorders of the Autonomic Nervous System
Raynaud's disease, also known as Raynaud's...
Measurement of Blood Pressure

