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Updated: Nov 1, 2025

Preparation of Monodomain Liquid Crystal Elastomers and Liquid Crystal Elastomer Nanocomposites
Published on: February 6, 2016
Methoxy terminated poly dimethylsiloxane bonded stationary phase for reversed-phase liquid chromatography
Dandan Guo1, Tingfeng Tang2, Shaohua Huang3
1Institute of Drug Discovery Technology, Ningbo University, Ningbo 315211, China; Department of Chemistry, Xixi Campus, Zhejiang University, Hangzhou 310028, China.
Abstract:
In this work, a methoxy terminated poly dimethylsiloxane modified silica gel material was proposed as a novel stationary phase for reversed-phase liquid chromatography. With 5 μm silica gel as matrix, methoxy terminated poly dimethylsiloxane polymer was grafted by one step chemical bonding reaction. The obtained stationary phase was characterized by scanning electron microscopy, fourier transform infrared spectroscopy and element analysis. To our knowledge, this is the novel methoxy terminated poly dimethylsiloxane bonded stationary phase with good separation efficiency (42107-46988 plates/m for benzene homologues) and high stability (RSD is 0.08-5.09%). Comparing to other traditional columns of the same type, the proposed stationary phase has a wider polarity separation scale and shorter analysis time. In addition to the rapid separation of hydrophobic compound, such column also exhibited great potential in the separation of hydrophilic analytes.
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