Ischemic Stroke Associated With Ovarian Hyperstimulation Syndrome.

Area of Science:

• Reproductive Medicine
• Neurology
• Emergency Medicine

Background:

• Ovarian hyperstimulation syndrome (OHSS) is a significant complication of assisted reproductive technology (ART).
• Severe OHSS can lead to thromboembolic events and, rarely, ischemic stroke.
• Early recognition and management are crucial for preventing severe outcomes.

Observation:

• A 32-year-old woman with a history of OHSS presented with acute impaired consciousness.
• Initial assessment in the emergency department was limited due to the patient's condition.
• Diffusion-weighted MRI confirmed ischemic stroke after initial negative noncontrast CT.

Findings:

• Ischemic stroke is a rare but serious neurological complication of OHSS.
• Young women undergoing fertility treatments are at increased risk.
• Neurological symptoms in OHSS patients warrant a high index of suspicion for stroke.

Implications:

• Emergency physicians must consider stroke in young women with OHSS presenting with neurological deficits.
• Prompt diagnosis and intervention are critical to minimize long-term sequelae.
• Increased awareness can improve patient outcomes and reduce morbidity associated with OHSS.