Genome Warehouse: A Public Repository Housing Genome-scale Data

Area of Science:

• Genomics
• Bioinformatics
• Data Management

Background:

• The Genome Warehouse (GWH) is a key resource within the National Genomics Data Center (NGDC) at the China National Center for Bioinformation (CNCB).
• It serves as a public repository for genome assembly data, supporting diverse species and assembly levels.
• GWH facilitates genome data submission, storage, release, and sharing through various web services.

Purpose of the Study:

• To establish a comprehensive public repository for genome assembly data.
• To provide standardized procedures for data submission, quality control, and metadata collection.
• To enable free and public access to genome sequences and annotations for global research.

Main Methods:

• Acceptance of full and partial genome sequences (chloroplast, mitochondrion, plasmid) with varying assembly levels.
• Collection of detailed metadata including biological project, sample, and assembly information.
• Implementation of uniform quality control procedures for high-quality data archiving.
• Utilization of JBrowse for visualization of released genome sequences and annotations.

Main Results:

• As of May 21, 2021, GWH received 19,124 direct submissions from 1108 species.
• A total of 8,772 genome assemblies have been released.
• The repository houses diverse genome assembly data with associated metadata and annotations.

Conclusions:

• GWH is a vital resource for genome-scale data management.
• It provides essential, publicly accessible data to support worldwide research activities.
• The platform ensures data quality and facilitates global genomic research collaboration.