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Updated: Nov 1, 2025

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3D Modeling of the Lateral Ventricles and Histological Characterization of Periventricular Tissue in Humans and Mouse
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Prognostic Analysis and Risk Factors Associated with Fetal Ventriculomegaly
Qi-Ming Li1,2, Hong-Zhan Liao3, Wen-Bo Wang3
1Department of Neurosurgery, Taihe Hospital, Shiyan, China, 122747332@qq.com.
Pediatric Neurosurgery
|June 27, 2021
Summary
Fetal lateral ventriculomegaly (VM) prognosis can be predicted by monitoring the change speed of width ratio (CSWR) and maximum lateral ventricular width (MW). These metrics aid in assessing outcomes for fetuses with VM.
Area of Science:
- Medical Imaging
- Fetal Medicine
- Neurology
Background:
- Fetal lateral ventriculomegaly (VM) is a condition requiring investigation into its clinical outcomes.
- Identifying risk factors associated with fetal VM is crucial for prenatal care.
Purpose of the Study:
- To investigate the clinical outcome of fetal lateral ventriculomegaly (VM).
- To identify risk factors influencing the prognosis of fetal VM.
Main Methods:
- Retrospective analysis of 255 cases diagnosed with fetal VM.
- Prenatal imaging and follow-up investigations were conducted.
- Multivariate logistic regression analyzed factors affecting hydrocephalus prognosis.
Main Results:
- 102 cases were followed up; 12 had poor prognosis (case group) and were compared to controls.
- Change speed of width ratio (CSWR) and maximum lateral ventricular width (MW) were statistically significant.
- CSWR and MW were associated with fetal prognosis.
Conclusions:
- Change speed of width ratio (CSWR) and maximum lateral ventricular width (MW) show potential value in predicting fetal prognosis.
- These imaging metrics may assist in managing fetuses diagnosed with VM.
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