Mini Review: Virus Interference: History, Types and Occurrence in Crustaceans
César Marcial Escobedo-Bonilla1
1Laboratory of Pathology and Molecular Diagnostics, Aquaculture Department, Instituto Politécnico Nacional - CIIDIR Unidad Sinaloa, Guasave, Mexico.
Frontiers in Immunology
|June 28, 2021
Summary
Virus interference, where one virus inhibits another, offers a natural defense against infections in various hosts. This phenomenon is being revisited for potential applications in aquaculture and medicine.
Area of Science:
- Virology
- Immunology
- Aquaculture
Background:
- Virus interference is a natural phenomenon where co-infecting viruses modulate each other's replication within a host.
- Historically studied from the 18th century, research intensified between 1930-1960, focusing on bacterial and vertebrate viruses.
- Pathogenic viruses involved in interference impact human and animal health, suggesting therapeutic potential.
Purpose of the Study:
- To review the historical context and scientific understanding of virus interference.
- To highlight recent research on virus interference in commercially important farmed aquatic species, particularly crustaceans.
- To emphasize the potential of virus interference as an alternative to chemical therapies.
Main Methods:
- Historical literature review of virus interference studies.
- Analysis of experimental data from in vivo, tissue, and cell culture assays.
- Examination of recent studies on virus interference in crustacean aquaculture.
Main Results:
- Virus interference has been observed across diverse hosts, including bacteria, vertebrates, and invertebrates.
- Certain viruses affecting farmed crustaceans exhibit interference phenomena.
- Interference can significantly reduce the severity and mortality caused by superinfecting viruses.
Conclusions:
- Virus interference presents a promising avenue for developing novel, non-chemical therapeutic strategies against viral diseases.
- Further research into virus interference in aquaculture is crucial for disease management and sustainable production.
- Understanding interference mechanisms can lead to innovative approaches in both medicine and animal health.
Keywords:
bacteria hostscell culturescrustacean hoststissue culturesvertebrate hostsvirus interferenceMore Related Videos
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