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WIfI classification: the Society for Vascular Surgery lower extremity threatened limb classification system, a
Lorena de Oliveira Cerqueira1, Eliud Garcia Duarte1,2,3,4, André Luis de Souza Barros1,2
1Universidade Vila Velha - UVV, Cirurgia Vascular, Vila Velha, ES, Brasil.
Insights
The new Wound, Ischemia, and foot Infection (WIfI) classification system aids in assessing threatened lower limb risk. Validation studies confirm its effectiveness in predicting amputation and guiding limb salvage strategies.
Area of Science:
- Vascular Surgery
- Lower Limb Revascularization
- Diabetic Foot Complications
Background:
- The Society for Vascular Surgery developed the Wound, Ischemia, and foot Infection (WIfI) classification.
- This system addresses threatened lower limb risk, including complex diabetic cases previously excluded from critical limb ischemia concepts.
- It aims for accurate, early risk stratification to guide clinical management and therapy comparison.
Purpose of the Study:
- To synthesize key findings on the WIfI classification from existing scientific literature.
- To consolidate evidence supporting the WIfI system's utility in managing threatened lower limbs.
- To provide a comprehensive overview of WIfI classification research.
Main Methods:
- Literature review of studies validating the WIfI classification system.
- Analysis of research focusing on WIfI's association with limb salvage outcomes.
- Synthesis of data from multiple validation studies.
Main Results:
- WIfI classification is strongly associated with amputation rates and amputation-free survival.
- The system effectively predicts the need for reintervention and stenosis (RAS) events.
- Studies demonstrate WIfI's utility in predicting wound healing outcomes.
Conclusions:
- The WIfI classification system is a validated tool for risk stratification in threatened lower limbs.
- It aids in predicting amputation risk and guiding limb salvage interventions.
- The WIfI system offers a standardized approach for managing complex lower limb ischemia, including in diabetic patients.
Abstract:
The Society for Vascular Surgery has proposed a new classification system for the threatened lower limb, based on the three main factors that have an impact on limb amputation risk: Wound (W), Ischemia (I) and foot Infection ("fI") - the WIfI classification. The system also covers diabetic patients, previously excluded from the concept of critical limb ischemia because of their complex clinical condition. The classification's purpose is to provide accurate and early risk stratification for patients with threatened lower limbs; assisting with clinical management, enabling comparison of alternative therapies; and predicting risk of amputation at 1 year and the need for limb revascularization. The objective of this study is to collect together the main points about the WIfI classification that have been discussed in the scientific literature. Most of the studies conducted for validation of this classification system prove its association with factors related to limb salvage, such as amputation rates, amputation-free survival, prediction of reintervention, amputation, and stenosis (RAS) events, and wound healing.
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