Post-Biopsy Pneumothorax Incidence in Patients Treated with Biosentry™ Plug Device

Area of Science:

• Interventional Radiology
• Pulmonary Medicine
• Medical Device Technology

Background:

• Pneumothorax is a potential complication following lung biopsies.
• The Biosentry™ Plug Device (BPD) was developed as a prophylactic sealant to mitigate this risk.
• Evaluating the efficacy of BPD in clinical practice is crucial for patient safety.

Purpose of the Study:

• To assess the effectiveness of the Biosentry™ Plug Device (BPD) in reducing pneumothorax rates after lung biopsies.
• To compare the incidence of pneumothorax and other complications in patients who received a BPD versus those who did not.
• To determine if BPD usage influences the severity of post-biopsy complications.

Main Methods:

• A retrospective cohort study was conducted at a single institution.
• Data from 521 patients undergoing lung biopsies between May 2015 and August 2017 were analyzed.
• Patient demographics, clinical factors, and BPD usage were recorded; chi-squared analysis was employed.

Main Results:

• Out of 521 patients, 74 (14.2%) received the BPD, and 447 (85.8%) did not.
• A total of 190 patients (36.4%) experienced pneumothorax within one month post-biopsy.
• Pneumothorax rates were similar between BPD (35.1%) and non-BPD (36.7%) groups (p=0.7970).

Conclusions:

• The Biosentry™ Plug Device (BPD) did not demonstrate a significant reduction in pneumothorax incidence after lung biopsies.
• The findings suggest that BPD may not effectively limit the severity of complications associated with lung biopsies.
• Further research may be warranted to explore alternative prophylactic measures or refine BPD application.