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Related Experiment Video

Updated: Nov 1, 2025

Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice

Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice

Published on: October 10, 2025

COVID-19 and Pregnancy: A Case Study.

Rui Long¹, Di Wu¹, Xingguang Lin¹

¹Department of Obstetrics Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 China.

Global Challenges (Hoboken, NJ)

|June 28, 2021

Summary

This summary is machine-generated.

This case study reports on a pregnant woman with SARS-CoV-2 exposure who delivered a healthy infant. Continuing pregnancy to term, despite COVID-19, may reduce infant complications.

Keywords:

COVID‐19 IgG birth induction vertical transmission

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Last Updated: Nov 1, 2025

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Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic PolyI:C

Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic PolyI:C

Published on: March 25, 2016

Area of Science:

Obstetrics and Gynecology
Infectious Diseases
Neonatology

Background:

The global spread of 2019 novel coronavirus disease (COVID-19) raises concerns for pregnant women and infants due to their unique immune statuses.
Special attention is warranted for pregnant individuals and newborns concerning SARS-CoV-2 infection.

Purpose of the Study:

To report a case of a pregnant woman exposed to SARS-CoV-2 who continued her pregnancy to term.
To observe the outcomes for both mother and neonate following delivery.

Main Methods:

A case report detailing a pregnant woman exposed to SARS-CoV-2 at 34+1 weeks gestation.
Monitoring of maternal and neonatal health status through delivery and a three-month follow-up.
Neonatal testing included immunoglobulin G (IgG) and nucleic acid tests for SARS-CoV-2.

Main Results:

The pregnant woman remained asymptomatic and delivered a healthy infant at 37+5 weeks gestation.
The neonate tested positive for SARS-CoV-2 immunoglobulin G (IgG) but negative for nucleic acid.
Both mother and infant experienced positive recovery and were well at the three-month follow-up.

Conclusions:

Continuing pregnancy to term, rather than preterm delivery, may mitigate severe perinatal and infant complications.
Further research is necessary to definitively establish the occurrence and implications of vertical transmission of SARS-CoV-2.