Pediatric Multisystem Inflammatory Syndrome in Children as a Challenging Problem for Pediatric Surgeons in the COVID

Beata Jurkiewicz1, Magdalena Szymanek-Szwed1, Piotr Hartmann2

  • 1Department of Pediatric Surgery and Pediatric Urology, Medical Center of Postgraduate Education, Dziekanów Leśny, Poland.

Insights

Pediatric inflammatory multisystem syndrome (PIMS-TS) can cause severe abdominal symptoms mimicking surgical emergencies in children infected with SARS-CoV-2. Early consideration of PIMS-TS is crucial for accurate diagnosis and timely management in pediatric patients.

Area of Science:

  • Pediatric Infectious Diseases
  • Pediatric Surgery
  • Critical Care Medicine

Background:

  • Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) primarily impacted adults, with children often experiencing milder symptoms.
  • Emergence of pediatric inflammatory multisystem syndrome (PIMS-TS) in children post-SARS-CoV-2 infection, presenting with severe systemic inflammation.
  • PIMS-TS can manifest with symptoms suggestive of surgical emergencies, complicating diagnosis and management.

Observation:

  • A case report details an 11-year-old boy with severe abdominal pain and peritonitis symptoms requiring surgery.
  • Post-operative diagnosis revealed PIMS-TS, highlighting the syndrome's potential surgical presentations.
  • Symptoms included severe abdominal pain, peritoneal signs, ascites, elevated inflammatory markers, and intestinal inflammation.

Findings:

  • PIMS-TS can present with acute abdominal symptoms, mimicking surgical conditions like appendicitis or peritonitis.
  • The syndrome carries a significant mortality rate (up to 2%) and requires prompt recognition.
  • Diagnostic challenges arise due to the overlap of gastrointestinal and inflammatory symptoms.

Implications:

  • PIMS-TS should be included in the differential diagnosis for acute abdominal pain in children, especially with a history of SARS-CoV-2 exposure.
  • Increased awareness among pediatricians and surgeons is vital for timely diagnosis and appropriate treatment strategies.
  • Further research is needed to elucidate the pathophysiology and optimize management protocols for PIMS-TS with surgical manifestations.