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Ability of SARC-F to Find Probable Sarcopenia Cases in Older Adults
D Erbas Sacar1, C Kilic, M A Karan
1Gulistan Bahat, Istanbul University, Istanbul Medical School, Department of Internal Medicine, Capa, 34390, Istanbul, Turkey, Telephone: + 90 212 414 20 00-33204, Fax: + 90 212 532 42 08,
Background/Objective:
In 2018 EWGSOP2 has suggested low muscle strength as the primary parameter of sarcopenia. The consensus has recommended SARC-F questionnaire as a screening test to find cases with low muscle strength which has been designated as probable sarcopenia. We aimed to study the ability of SARC-F to find probable sarcopenia cases in older patients.
Design:
Retrospective, cross-sectional.
Setting:
Istanbul University Istanbul Faculty of Medicine.
Participants:
A total of 456 older adults (71.1% female, mean age: 74.6±6.6 years).
Measurements:
We diagnosed probable sarcopenia by EWGSOP 2 criteria, i.e., presence of low handgrip strength (HGS). SARC-F questionnaire was performed by all participants. We used a receiver operating characteristics curve to obtain SARC-F cut-off values to detect probable sarcopenia and calculated the area under the curve and 95% confidence interval (CI).
Results:
We included 456 participants (71.1% female; mean age: 74.6 ± 6.6 years). Probable sarcopenia was present in 58 (12.7%). SARC-F cut-off ≥ 2 presented the best balance between sensitivity and specificity (sensitivity: 64.9% vs specificity: 67.9%) to detect probable sarcopenia [the area under the receiver operating characteristics curve (AUC) = 0.710; 95% Cl: 0.660-0.752, p< 0.001]. SARC-F with a cut-off point ≥ 1 had sensitivity 84.2% and specificity 40.5% and SARC-F ≥ 4 had high specificity 88.2% with 40.3% sensitivity.
Conclusion:
SARC-F is a good screening tool for sarcopenia in practice. Our findings suggest SARC-F ≥ 1 cut-off point to be used as the probable sarcopenia screening tool regarding its high sensitivity. Consequently, SARC-F ≥ 4 cut-off is better to be used if one prefers to exclude probable sarcopenia.
