A new triarylindanone and a new isobenzofuranone derivative from Selaginella tamariscina
Yu-Jie Peng1, Dan Zhang1, Wan-Ling Chen1
1Key Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province, School of Medicine, Hunan Normal University, Changsha, Hunan, PR China.
Natural Product Research
|June 28, 2021
Abstract:
A new triarylindanone, namely selagindanone A (1), and a new isobenzofuranone (2), 3,4-bis(4-hydroxyphenyl)isobenzofuran-1(3H)-one, were isolated from Selaginella tamariscina. Their structures were elucidated by comprehensive spectroscopic and mass spectrometric analyses, including 1 D-, 2 D-NMR and HR-ESI-MS. Compound 1 possesses a unique structural feature of triaryl-substituted in the skeleton of 1-indanone. In addition, compound 2 showed weak cytotoxicity against human hepatocellular carcinoma SMMC-7721 and HepG2 cell lines.
Keywords:
3,4-bis(4-hydroxyphenyl)isobenzofuran-1(3H)-oneSelaginella tamariscinacytotoxicityisobenzofuranoneselagindanone Atriaylindanone
