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Updated: Oct 31, 2025

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Coronary artery changes in congenital coronary-cameral fistulas evaluated by computed tomographic angiography
Suvipaporn Siripornpitak1,2, Apichaya Sriprachyakul3,4, Worakan Promphan5
1Faculty of Medicine, Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Phayatai, Ratchathewi, Bangkok, 10400, Thailand. ssiripornpitak@yahoo.com.
Insights
Congenital coronary-cameral fistula (cCCF) often involves large coronary aneurysms. While fistula features don't predict aneurysms, closure reduces coronary artery size but carries a risk of thrombosis.
Area of Science:
- Cardiovascular Imaging
- Pediatric Cardiology
- Congenital Heart Disease
Background:
- Congenital coronary-cameral fistula (cCCF) is a rare condition involving abnormal connections between coronary arteries and heart chambers.
- Understanding the characteristics of cCCF and its impact on coronary arteries is crucial for effective management.
Purpose of the Study:
- To evaluate coronary artery diameter and aneurysm prevalence in cCCF.
- To identify factors associated with coronary artery aneurysm formation.
- To assess changes in coronary arteries post-fistula closure using computed tomography (CT).
Main Methods:
- Retrospective review of CT findings in 25 patients with cCCF.
- Analysis of fistula origins, terminations, length, complexity, and Sakakibara classification.
- Measurement of coronary artery Z scores and assessment of aneurysm presence and size.
Main Results:
- Aneurysms were present in 52% of cases, with giant aneurysms (68%) being common.
- No significant risk factors for aneurysm development were identified.
- Following fistula closure, coronary artery Z scores decreased significantly (p=0.006), and coronary thrombosis occurred in 23% of patients.
Conclusions:
- Large coronary aneurysms are a frequent finding in cCCF.
- No specific fistula characteristics predict aneurysm formation.
- Fistula closure leads to reduced coronary artery diameter but poses a risk of coronary thrombosis.
Purpose:
The study sought to determine coronary artery diameter in congenital coronary-cameral fistula (cCCF), factors associated with coronary artery aneurysm, coronary artery changes after fistula closure, and computed tomographic (CT) findings after treatment.
Materials And Methods:
We retrospectively reviewed CT findings of the cCCF for origins, terminations, fistula length, complexities, and Sakakibara classification. Coronary artery diameter was expressed as coronary artery Z score. Fistula features associated with coronary artery aneurysm were analyzed. Post-fistula closures were analyzed for coronary artery dilatation, coronary thrombosis, complete fistula closure, and fistula thrombosis.
Results:
Twenty-five patients (median age 33 months, interquartile range, IQR 25-48) were included. Coronary feeders and terminations were frequently right coronary artery (48%) and right ventricle (56%), respectively. Fistula aneurysm occurred in 52% of cases. Mean coronary artery Z score was 13.03 ± 6.36 with a high incidence of giant coronary artery aneurysm (68%). We found no statistically significant risk factors associated with coronary artery aneurysm (p value range 0.075-0.370). Median duration of the follow-up CT after closure of the fistulas was 6.4 months (IQR 5.0-8.7). Coronary artery Z score significantly decreased by 0.82 (IQR 0.28-1.35), p = 0.006 and coronary thrombosis occurred in 23% of cases during follow-up.
Conclusions:
Large coronary aneurysm is common in cCCF. No characteristic feature of the fistula influencing coronary artery aneurysm is identified. There is a diminution in coronary artery Z score after fistula closure. Coronary thrombosis is a major complication after treatment.
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