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Peptide Mini-Vectors for Gene Delivery
Robert G Cooper1, Richard P Harbottle2, Holm Schneider2
1The Imperial College Genetic Therapies Centre Department of Chemistry, Imperial College of Science, Technology & Medicine, South Kensington, London SW7 2AY (UK), Fax: (+44) 171-594-5803.
Angewandte Chemie (International Ed. in English)
|June 29, 2021
Abstract:
The effective treatment of diseases by gene therapy may be a step nearer with the synthesis of two new peptide-based vectors for the delivery of genes to cells. A combination of two peptides-one containing an Arg-Gly-Asp integrin-binding motif, the other a fusogenic moiety-delivers genes almost as effectively as cationic liposomes.

