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Clinical research: low-level laser therapy in accelerating orthodontic tooth movement
1Department of Orthodontics, School of Stomatology, Capital Medical University, No. 4, Tiantanxili, Beijing, China.
BMC Oral Health
|June 29, 2021
Summary
Low-level laser therapy (LLLT) significantly accelerated orthodontic tooth movement by altering bone metabolism markers in gingival crevicular fluid (GCF). This laser treatment increased interleukin-1β (IL-1β) and RANKL while decreasing osteoprotegerin (OPG).
Area of Science:
- Orthodontics
- Biotechnology
- Laser Therapy
Background:
- Investigating low-level laser therapy (LLLT) effects on orthodontic tooth movement.
- Correlating LLLT with key biomarkers in gingival crevicular fluid (GCF).
- Examining interleukin-1β (IL-1β), RANKL, and osteoprotegerin (OPG) levels.
Purpose of the Study:
- To evaluate the impact of LLLT on the speed of orthodontic tooth movement.
- To assess changes in GCF biomarkers (IL-1β, RANKL, OPG) following LLLT.
- To understand the relationship between LLLT, bone metabolism, and tooth movement.
Main Methods:
- Split-mouth design involving 12 patients undergoing premolar extraction.
- Application of diode laser (810 nm) on experimental sides on days 0, 7, 14, and 21.
- Analysis of GCF for IL-1β, RANKL, and OPG; intraoral scanning for tooth movement assessment.
Main Results:
- Significantly greater cumulative tooth movement in the LLLT group over 28 days.
- Reduced OPG levels and increased IL-1β and RANKL levels in GCF on laser-treated sides.
- Evidence of altered bone metabolism markers associated with accelerated tooth movement.
Conclusions:
- LLLT, with the parameters used, can modify bone metabolism.
- This modification has the potential to accelerate orthodontic tooth movement.
- Further research into LLLT parameters for optimizing orthodontic treatment is warranted.
