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Related Concept Videos

Sutures of the Skull01:22

Sutures of the Skull

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The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
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Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
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Related Experiment Video

Updated: Oct 31, 2025

A Mouse Distraction Osteogenesis Model
04:24

A Mouse Distraction Osteogenesis Model

Published on: November 14, 2018

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Distraction osteogenesis in craniosynostosis.

Henya Sandhaus1, Matthew D Johnson

  • 1Department of Otolaryngology, Head and Neck Surgery, Southern Illinois University School of Medicine, Springfield, Illinois, USA.

Current Opinion in Otolaryngology & Head and Neck Surgery
|June 29, 2021
PubMed
Summary
This summary is machine-generated.

Distraction osteogenesis (DO) offers benefits for craniosynostosis by increasing intracranial volume and improving aesthetics. This evolving surgical technique shows promise for various craniosynostosis types, though long-term data is pending.

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Area of Science:

  • Craniofacial Surgery
  • Pediatric Neurosurgery
  • Biomedical Engineering

Background:

  • Craniosynostosis involves premature cranial suture fusion, leading to developmental issues like increased intracranial hypertension.
  • Standard cranial vault remodeling has limitations; distraction osteogenesis (DO) presents an evolving alternative.
  • DO offers benefits for managing complications such as exophthalmos and upper airway obstruction.

Purpose of the Study:

  • To provide an overview and update on the surgical applications of distraction osteogenesis (DO) for craniosynostosis.
  • To highlight the advantages of DO compared to traditional cranial vault remodeling.
  • To discuss the current status and future considerations for DO in treating craniosynostosis.

Main Methods:

  • Review of existing literature on distraction osteogenesis techniques for craniosynostosis.
  • Analysis of DO applications in single and multisuture craniosynostosis, including cases with midface hypoplasia.
  • Examination of modified surgical procedures incorporating DO.

Main Results:

  • Distraction osteogenesis has been successfully applied to various craniosynostosis types, including single and multisuture forms.
  • DO effectively increases intracranial volume, reduces intracranial hypertension, and improves aesthetic outcomes.
  • Modified surgical approaches utilizing DO have maintained surgical goals while mitigating risks.

Conclusions:

  • Distraction osteogenesis is a developing surgical technique for syndromic and nonsyndromic craniosynostosis.
  • DO demonstrates significant benefits in managing craniosynostosis.
  • Further long-term data is needed to fully establish the efficacy and role of DO procedures.