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Shreesha Rao D S1, Mikkel Jensen1, Lars Grüner-Nielsen1

  • 1DTU Fotonik, Dept. of Photonics Engineering, Technical University of Denmark, Ørsteds Plads, 2800, Kongens Lyngby, Denmark.

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Summary
This summary is machine-generated.

We developed a low-noise supercontinuum source for spectral domain optical coherence tomography (SD-OCT). This breakthrough enables shot-noise limited detection, significantly improving OCT image quality and penetration depth.

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Area of Science:

  • Biomedical Optics
  • Optical Imaging
  • Laser Physics

Background:

  • Supercontinuum-based spectral domain optical coherence tomography (SD-OCT) has been limited by high pulse-to-pulse relative intensity noise.
  • Existing SD-OCT systems struggle to achieve shot-noise limited detection due to noisy supercontinuum sources.

Purpose of the Study:

  • To demonstrate shot-noise limited supercontinuum-based SD-OCT.
  • To develop a low-noise supercontinuum source for improved OCT performance.
  • To overcome the limitations of current supercontinuum sources in SD-OCT.

Main Methods:

  • Developed a novel low-noise supercontinuum source using an all-normal dispersion (ANDi) fiber pumped by a femtosecond laser.
  • Compared the noise performance of the 90 MHz ANDi fiber-based source with commercial 80 MHz and 320 MHz sources.
  • Performed SD-OCT imaging of biological tissues (skin, retina) and multilayer stacks.

Main Results:

  • Achieved shot-noise limited performance in supercontinuum-based SD-OCT with an axial resolution of 5.9 μm at 1370 nm.
  • The developed low-noise ANDi fiber source significantly improved OCT image contrast, sensitivity, and penetration depth.
  • Demonstrated superior noise performance compared to commercial supercontinuum sources.

Conclusions:

  • Supercontinuum-based SD-OCT can successfully operate in the shot-noise limited detection regime.
  • The developed low-noise supercontinuum source enables high-quality OCT imaging of various biological samples.
  • This advancement opens new possibilities for advanced optical coherence tomography applications.