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Published on: July 11, 2025
Understanding, explaining, and utilizing medical artificial intelligence
Romain Cadario1, Chiara Longoni2, Carey K Morewedge2
1Rotterdam School of Management, Erasmus University, Rotterdam, the Netherlands. cadario@rsm.nl.
People resist medical artificial intelligence (AI) due to perceived complexity and overconfidence in human doctors. Increasing understanding of AI decision-making boosts user trust and adoption of AI healthcare tools.
Area of Science:
- Medical Artificial Intelligence
- Human-Computer Interaction
- Behavioral Economics
Background:
- Medical artificial intelligence (AI) offers cost-effectiveness and scalability, often surpassing human performance.
- Despite AI's potential, public reluctance to utilize these technologies persists.
- Understanding the drivers of this resistance is crucial for AI adoption in healthcare.
Purpose of the Study:
- To investigate the psychological factors underlying resistance to medical AI.
- To examine the role of perceived understanding of decision-making processes (both human and algorithmic) in AI utilization.
- To test interventions aimed at increasing acceptance of AI in healthcare.
Main Methods:
- Five pre-registered experiments (N=2,699) assessed understanding of human vs. algorithmic medical decision-making.
- Studies manipulated perceived understanding and measured willingness to use AI providers.
- A large-scale field study (N=14,013) evaluated intervention effectiveness via Google Ads for a skin cancer detection app.
Main Results:
- Participants demonstrated an illusory understanding of human medical decision-making.
- This illusory understanding led to a preference for human providers over AI, increasing reluctance to use AI.
- Interventions enhancing the perceived understanding of AI processes significantly increased willingness to utilize AI healthcare providers.
- Intervention effectiveness was confirmed in a real-world online setting.
Conclusions:
- Resistance to medical AI stems from a combination of the 'black box' problem and an overestimation of understanding human decision-making.
- Brief interventions focused on demystifying AI processes can effectively enhance user trust and willingness to adopt AI healthcare solutions.
- These findings have significant implications for the design and implementation of AI technologies in clinical practice and public health campaigns.
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