Mechanism of molybdate insertion into pterin-based molybdenum cofactors

Corinna Probst1, Jing Yang2, Joern Krausze1

  • 1Institute of Plant Biology, Technische Universität Braunschweig, Braunschweig, Germany.

Nature Chemistry
|June 29, 2021
PubMed
Summary

Researchers elucidated the final step in molybdenum cofactor (Moco) synthesis, identifying Moco-AMP as a key intermediate. This discovery reveals the mechanism of molybdate insertion into molybdopterin, crucial for Moco-dependent enzymes.

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