Related Experiment Video
Updated: Oct 31, 2025

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
Exercise Dynamic of Patients with Chronic Heart Failure and Reduced Ejection Fraction
Sara Rovai1, Irene Mattavelli1, Elisabetta Salvioni1
1Centro Cardiologico Monzino, IRCCS, Via Parea 4, 20138, Milan, Italy.
Purpose Of Review:
Exercise causes various dynamic changes in all body parts either in healthy subject or in heart failure (HF) patients. The present review of current knowledge about HF patients with reduced ejection fraction focuses on dynamic changes along a "metabo-hemodynamic" perspective.
Recent Findings:
Studies on the dynamic changes occurring during exercise span many years. Thanks to the availability of advanced methods, it is nowadays possible to properly characterize respiratory, hemodynamic, and muscular function adjustments and their mismatch with the pulmonary and systemic circulations. Exercise is a dynamic event that involves several body functions. In HF patients, it is important to know at what level the limitation takes place in order to better manage these patients and to optimize therapeutic strategies.
Related Concept Videos
Pathophysiology of Heart Failure
Heart Failure VII: Nursing Interventions
Heart Failure V: Medical Management
Heart Failure VI: Adjunct Therapies
Heart Failure II: Pathophysiology
Heart Failure IV: Classification and Diagnostic Evaluation

