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"Everyone's Responsibility and No-One's Responsibility": A Thematic Analysis of a Roundtable on the Complex Problem of Secondary Stroke Prevention in Australia.

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Related Experiment Video

Updated: Oct 31, 2025

A Rehabilitation Program of Exoskeleton-assisted Body Weight-Supported Treadmill Training with Non-immersive Virtual Reality for Stroke Patients
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Interventions for reducing sedentary behaviour in people with stroke.

David H Saunders1, Gillian E Mead2, Claire Fitzsimons1

  • 1Physical Activity for Health Research Centre (PAHRC), University of Edinburgh, Edinburgh, UK.

The Cochrane Database of Systematic Reviews
|June 29, 2021
PubMed
Summary

Interventions to reduce sedentary time in stroke survivors did not significantly impact mortality, cardiovascular events, or falls. More high-quality research is needed to guide effective strategies for reducing sedentary behavior post-stroke.

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Area of Science:

  • Neurology
  • Rehabilitation Medicine
  • Public Health

Background:

  • Stroke survivors often experience prolonged sedentary periods, increasing cardiometabolic risk and impacting functional recovery.
  • Reducing sedentary time and increasing physical activity are crucial for preventing secondary cardiovascular events and mortality after stroke.

Purpose of the Study:

  • To evaluate the effectiveness of interventions aimed at reducing sedentary behavior in stroke survivors.
  • To determine if these interventions can decrease mortality, secondary vascular events, cardiovascular risk, and sedentary time.

Main Methods:

  • A systematic review and meta-analysis of randomized controlled trials (RCTs) were conducted.
  • Searches included major databases (Cochrane Stroke, CENTRAL, MEDLINE, Embase, etc.) up to December 2019.
  • Included RCTs compared interventions to reduce sedentary time against control groups.

Main Results:

  • Ten studies with 753 participants were included; most had high or unclear risk of bias.
  • Interventions showed no significant effect on mortality, recurrent vascular events, or falls (low-certainty evidence).
  • Sedentary time was not significantly reduced (very low-certainty evidence), and data on cardiometabolic risk factors were limited.

Conclusions:

  • Current evidence is insufficient to guide interventions for reducing sedentary behavior specifically in stroke survivors.
  • High-quality RCTs are needed, focusing on participants with mobility limitations, longer interventions, and objective outcome measures.
  • Further research should investigate long-term effects on sedentary patterns and cardiometabolic risk factors.