Related Experiment Video
Updated: Oct 31, 2025

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
Modern computational intelligence based drug repurposing for diabetes epidemic
Sweta Mohanty1, Md Harun Al Rashid2, Chandana Mohanty1
1School of Applied Science, KIIT University, Bhubaneswar, Odisha, India.
Background And Aim:
Objectives are to explore recent advances in discovery of new antidiabetic agents using repurposing strategies and to discuss modern technologies used for drug repurposing highlighting diabetic specific web portal.
Methods:
Recent literature were studied and analyzed from various sources such as Scopus, PubMed, and IEEE Xplore databases.
Results:
Drugs like Niclosamideethanolamine, Methazolamide, Diacerein, Berberine, Clobetasol, etc. with possibility of repurposing to curb diabetes can be potential late-stage clinical candidates, providing access to information on pharmacology, formulation, and probable toxicity if any.
Conclusions:
With collaboration of artificial intelligence (AI) with pharmacology, the efficiency of drug repurposing can improve significantly.
Related Concept Videos
Glucagon-like Receptor Agonists
GLP-1, when administered in high doses intravenously, triggers insulin secretion, inhibits glucagon release, slows gastric emptying, reduces food intake, and restores normal insulin secretion. However, its rapid inactivation by...
Oral Hypoglycemic Agents: Biguanides and Glitazones
Oral Hypoglycemic Agents: Glinides
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin: Biosynthesis, Chemistry, and Preparation
Damage or functional impairment of β-cells inhibits insulin production, leading to diabetes. Diabetes treatment...
Drug Discovery: Overview

