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Published on: February 27, 2015
Twenty years of proteomics in radiation biology - a look back
1Institute of Radiation Biology and Institute for Biological and Medical Imaging, Helmholtz Center Munich, German Research Center for Environmental Health GmbH, Neuherberg, Germany.
Purpose:
The aim of this article is to describe the technical development in proteomics during the last two decades with the focus on its use in radiation biology. It is written from a subjective point of view and aims not to be a scientific review of the subject.
Conclusion:
Proteomics is a fast developing technique and it has already contributed greatly to our understanding of biological mechanisms following radiation exposure. Novel proteomics approaches can be used in adequately designed cellular and animal experiments and above all in big clinical trials to investigate effects of ionizing radiation in the future.
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