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Updated: Oct 31, 2025

A Label-free Technique for the Spatio-temporal Imaging of Single Cell Secretions
Published on: November 23, 2015
Nanostructured ZnO and ZnO: Pd with MXene overlayer SPR biosensors
V R Sudheer1,2, S R SarathKumar3, S Sankararaman1
1Department of Optoelectronics, University of Kerala, Karyavattom, Thiruvananthapuram, 695581 India.
Abstract:
The development of biosensors based on various novel techniques has become highly significant in the context of the outburst of a pandemic like COVID 19. The present work reports the theoretical modeling of two surface plasmon resonance (SPR) based biosensing probe configurations on optical fiber employing Metal/ZnO/MXene and Metal/ZnO: Pd/MXene. Maximum sensitivities of 19,400 nm/RIU and 8350 nm/RIU are calculated with Metal/ZnO/MXene and Metal/ZnO: Pd/MXene, respectively. The sensors are suitable for analytes with refractive index values ranging from 1.354 to 1.422. The refractive index of mucus and serum being in this range, the proposed biosensor, can be a potential tool for COVID-19 detection.
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