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Pressure-Controlled Volume-Guaranteed Ventilation Improves Respiratory Dynamics in Pediatric Patients During

Huan Liu1, Yuanyuan Cao1, Lei Zhang1

  • 1Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China.

International Journal of General Medicine
|June 30, 2021
PubMed

Insights

Pressure-controlled volume-guaranteed (PCV-VG) ventilation offers lower peak airway pressure and improved dynamic compliance in pediatric patients undergoing laparoscopic surgery compared to volume-controlled ventilation (VCV). This method may be superior for pediatric mechanical ventilation.

Area of Science:

  • Anesthesiology
  • Pediatric Critical Care
  • Respiratory Physiology

Background:

  • Pressure-controlled volume-guaranteed (PCV-VG) ventilation integrates features of pressure-controlled ventilation (PCV) and volume-controlled ventilation (VCV).
  • Previous studies in adults suggest PCV-VG can reduce airway pressures and enhance oxygenation.
  • This study investigates PCV-VG in pediatric patients undergoing laparoscopic surgery with laryngeal mask airway ventilation.

Observation:

  • A prospective, randomized clinical trial involving 64 pediatric patients compared PCV-VG and VCV.
  • Hemodynamic variables showed no significant differences between groups.
  • Key respiratory parameters, including peak airway pressure (Ppeak), plateau airway pressure, and pulmonary dynamic compliance (Cydn), were recorded at multiple intraoperative time points.

Findings:

  • PCV-VG significantly reduced Ppeak and plateau airway pressure compared to VCV.
  • Pulmonary dynamic compliance (Cydn) was significantly higher in the PCV-VG group.
  • No statistically significant differences in respiratory adverse events were observed between the VCV and PCV-VG groups.

Implications:

  • PCV-VG demonstrates potential as a superior mechanical ventilation strategy for pediatric patients undergoing laparoscopic procedures with laryngeal mask airways.
  • The findings suggest PCV-VG can optimize respiratory mechanics, potentially leading to improved patient outcomes.
  • Further research may explore long-term benefits and broader applications of PCV-VG in pediatric anesthesia.
Abstract

Keywords:
adverse eventsmechanical ventilationpediatric anesthesiapediatric intensive care

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