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Updated: Oct 31, 2025

Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer
Published on: March 1, 2015
Facial paralysis due to a spitting cobra bite.
Willem D Rinkel1, Richard Mastenbroek2, Pieter J Wismans3
1Department of Plastic-, Reconstructive- and Hand surgery, Utrecht University Medical Center, University of Utrecht, Utrecht, the Netherlands.
Snakebites cause growing global health issues, including facial paralysis. Mime therapy, a conservative approach, showed positive results in resolving neurotoxic-induced facial paralysis in a child, suggesting it can be a transient condition.
Area of Science:
- Neurology
- Toxicology
- Dermatology
Background:
- Snakebite envenomation is a significant global health concern, particularly its nonfatal consequences.
- The World Health Organization has reclassified snakebites as a Neglected Tropical Disease due to their increasing impact.
- Facial paralysis is a serious sequela of certain snakebites, necessitating effective treatment strategies.
Observation:
- A 4.5-year-old boy experienced right-sided facial paralysis following a spitting cobra bite, attributed to venom-induced neurotoxicity.
- The patient presented with significant local swelling and paralysis affecting the right side of his face.
- Conventional surgical interventions for facial paralysis include nerve repair, grafting, transfers, and muscle transplantation.
Findings:
- Mime therapy, a form of neuromuscular retraining, was employed as a conservative treatment.
- The child achieved good functional recovery with only moderate contour deficiency and subtle zygomatic muscle paresis at 1 year and 9 months post-treatment.
- This case highlights the potential for transient facial paralysis following snakebites.
Implications:
- Mime therapy can be an effective conservative treatment for snakebite-induced facial paralysis.
- The natural course of facial paralysis from envenomation may involve spontaneous resolution or significant improvement with non-surgical interventions.
- Further research into conservative management of snakebite sequelae is warranted to improve patient outcomes.
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