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Acute myocarditis during the COVID-19 pandemic: A single center experience

Matthew Petersen1, Borna Mehrad1,2, Ellen C Keeley1,3

  • 1Florida Department of Medicine, University of Florida, Gainesville, FL, United States of America.

American Heart Journal Plus : Cardiology Research and Practice
|June 30, 2021
PubMed

Insights

Acute myocarditis admissions increased during the COVID-19 pandemic. Patients testing positive for SARS-CoV-2 were older with lower troponin levels.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Epidemiology

Background:

  • Acute myocarditis is an inflammation of the heart muscle.
  • The coronavirus disease 2019 (COVID-19) pandemic may have impacted the incidence and presentation of various medical conditions.
  • Understanding changes in acute myocarditis during the pandemic is crucial for clinical management.

Purpose of the Study:

  • To compare the incidence and patient characteristics of acute myocarditis before and during the COVID-19 pandemic.
  • To investigate the association between SARS-CoV-2 infection and acute myocarditis.

Main Methods:

  • Retrospective chart review of patients diagnosed with acute myocarditis.
  • Data collection spanned from September 2017 to August 2020, encompassing pre-pandemic and early pandemic periods.
  • Analysis included admission rates and patient demographics, clinical features, and laboratory findings.

Main Results:

  • A significant increase in acute myocarditis admissions was observed during the initial six months of the pandemic (3.7/month) compared to the pre-pandemic period (1.5/month).
  • Out of 22 patients admitted during the pandemic, 10 (45%) tested positive for SARS-CoV-2.
  • Patients with confirmed SARS-CoV-2 infection were older and presented with lower peak troponin levels.

Conclusions:

  • The incidence of acute myocarditis admissions rose during the COVID-19 pandemic.
  • Less than half of patients admitted with acute myocarditis during the pandemic tested positive for SARS-CoV-2.
  • SARS-CoV-2 positive patients with acute myocarditis were characterized by older age and lower peak troponin levels.
Abstract

Keywords:
COVID-19MyocarditisSARS-CoV-2

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