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SARS-CoV-2 is associated with changes in brain structure in UK Biobank
COVID-19 infection is linked to brain changes, including grey matter reduction and cognitive decline, even in mild cases. These findings suggest potential mechanisms for brain pathology via olfactory pathways.
Area of Science:
- Neuroscience
- Infectious Diseases
- Radiology
Background:
- COVID-19 (caused by SARS-CoV-2) is associated with neurological abnormalities.
- The impact of milder SARS-CoV-2 infections on the brain and underlying mechanisms remain unclear.
Conclusions:
- Longitudinal brain changes and cognitive decline are evident in COVID-19 patients, including mild cases.
- Findings suggest potential neuroinflammatory or olfactory pathway-driven mechanisms for COVID-19 brain pathology.
- Further research is needed to determine the long-term effects and potential for recovery.
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