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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...

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Related Experiment Video

Updated: Oct 31, 2025

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Assessing migraine therapeutics

Cen Xu¹, Jeanine Bussiere¹

¹7129Amgen Inc., Thousand Oaks, CA, USA.

Cephalalgia : an International Journal of Headache

|June 30, 2021

Summary

No abstract available in PubMed .

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