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Updated: Oct 31, 2025

Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model
Published on: August 11, 2023
Bulbar watershed ischemic stroke: the comma-shaped sign-a case series
Elena Merli1, Michele Romoli1,2, Mauro Gentile1
1IRCCS Istituto Delle Scienze Neurologiche Di Bologna, Neurology and Metropolitan Stroke Center, Maggiore Hospital, Largo Nigrisoli 2, 40133, Bologna, Italy.
Abstract:
Watershed infarcts can involve the brainstem, with lesions distributed across the terminal supply from the vertebral and cerebellar arteries. Brain imaging can highlight a comma-shaped lesion at the edge of vertebral and posteroinferior cerebellar artery vascularization territory. Such peculiar MRI lesion shape might suggest a watershed hypoperfusion etiology and direct workup towards causes of hemodynamic impairment, including postural hypotension, cardiac failure, or vertebral artery origin occlusion.

