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Ability to detect potentially inappropriate prescribing in older patients: comparative analysis between PIM-Check and
Akram Farhat1,2,3, Alice Panchaud4, Amal Al-Hajje5
1Center for Research and Innovation in Clinical Pharmaceutical Sciences, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland. akram.farhat@hotmail.com.
Potentially inappropriate prescribing (PIP) tools PIM-Check and STOPP/START were compared. STOPP/START identified more PIP in older patients, particularly geriatric syndromes, while PIM-Check covered other areas.
Area of Science:
- Geriatric Medicine
- Pharmacology
- Drug Safety
Background:
- Potentially inappropriate prescribing (PIP) contributes to preventable adverse drug events in older adults.
- Accurate detection of PIP is crucial for improving patient outcomes in geriatric care.
Purpose of the Study:
- To conduct a comparative analysis, both qualitative and quantitative, of two tools for detecting PIP: PIM-Check and STOPP/START.
- To evaluate the concordance between PIM-Check criteria and the STOPP/START criteria.
Main Methods:
- Qualitative analysis of criterion concordance between PIM-Check and STOPP/START.
- Retrospective comparative observational study of PIP detection using both tools in 50 hospitalized older patients.
Main Results:
- 50% of STOPP/START criteria showed concordance with PIM-Check.
- PIP prevalence was 80% with PIM-Check and 90% with STOPP/START.
- PIM-Check identified more PIP in cardiology, angiology, nephrology, and endocrinology, while STOPP/START detected PIP related to geriatric syndromes.
Conclusions:
- PIM-Check has limitations in detecting PIP in frail geriatric populations, missing certain geriatric syndromes.
- PIM-Check offers complementary coverage in therapeutic areas not addressed by STOPP/START.
- Both tools are valuable but have distinct strengths for PIP detection in older adults.
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Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...