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A clinical case series of COVID-19-associated acute limb ischemia: real-world situation

Steven Philip Surya1, Rony Marethianto Santoso2

  • 1Primaya Hopsital Tangerang, Jl. MH. Thamrin no.3, Kebon Nanas, Cikokol, Tangerang, Indonesia. stevenphilip07@gmail.com.

The Egyptian Heart Journal : (EHJ) : Official Bulletin of the Egyptian Society of Cardiology
|June 30, 2021
PubMed

Insights

This case series highlights acute limb ischemia (ALI) as a rare but serious complication of COVID-19. Management challenges and the importance of clinical follow-up in pandemic situations are emphasized.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Vascular Surgery

Background:

  • COVID-19 can lead to cardiovascular complications, including hypercoagulation and immunothrombus formation.
  • Acute Limb Ischemia (ALI) is a rare but organ-threatening complication of COVID-19.
  • Lack of specific guidelines for managing ALI in COVID-19 patients presents diagnostic and therapeutic challenges.

Purpose of the Study:

  • To present a case series of two patients experiencing acute limb ischemia secondary to COVID-19.
  • To discuss the challenges in diagnosing and managing ALI during the COVID-19 pandemic.
  • To underscore the importance of clinical follow-up for ALI patients with COVID-19.

Main Methods:

  • Case series presentation of two patients with ALI complicating COVID-19.
  • Detailed description of patient demographics, comorbidities, clinical presentation, and treatment.
  • Analysis of treatment outcomes and contributing factors.

Main Results:

  • The first patient, an 80-year-old female, recovered with oral drug therapy despite initial reluctance for hospitalization.
  • The second patient, a 54-year-old female with multiple comorbidities, unfortunately passed away due to acute respiratory distress syndrome.
  • Both patients presented with lower extremity pain and cyanosis, indicative of ALI.

Conclusions:

  • Treatment of ALI in COVID-19 patients is complicated by various internal and external factors.
  • Diagnosis and management of ALI in COVID-19 may deviate from standard guidelines due to hospital regulations.
  • Close clinical follow-up is crucial for effective management of ALI in the context of COVID-19.
Abstract

Keywords:
Acute limb ischemiaCOVID-19COVID-19-associated coagulopathyCase reportImmunothrombus

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