Related Experiment Video
Updated: Oct 31, 2025

Ablation of a Neuronal Population Using a Two-photon Laser and Its Assessment Using Calcium Imaging and Behavioral Recording in Zebrafish Larvae
Published on: June 2, 2018
Understanding Neural Networks and Individual Neuron Importance via Information-Ordered Cumulative Ablation
Abstract:
In this work, we investigate the use of three information-theoretic quantities-entropy, mutual information with the class variable, and a class selectivity measure based on Kullback-Leibler (KL) divergence-to understand and study the behavior of already trained fully connected feedforward neural networks (NNs). We analyze the connection between these information-theoretic quantities and classification performance on the test set by cumulatively ablating neurons in networks trained on MNIST, FashionMNIST, and CIFAR-10. Our results parallel those recently published by Morcos et al., indicating that class selectivity is not a good indicator for classification performance. However, looking at individual layers separately, both mutual information and class selectivity are positively correlated with classification performance, at least for networks with ReLU activation functions. We provide explanations for this phenomenon and conclude that it is ill-advised to compare the proposed information-theoretic quantities across layers. Furthermore, we show that cumulative ablation of neurons with ascending or descending information-theoretic quantities can be used to formulate hypotheses regarding the joint behavior of multiple neurons, such as redundancy and synergy, with comparably low computational cost. We also draw connections to the information bottleneck theory for NNs.
More Related Videos
05:27Author Spotlight: Investigating the Mechanisms of Neural Circuit Assembly and Synapse Formation in Drosophila
Published on: July 26, 2024
12:27Large-scale Reconstructions and Independent, Unbiased Clustering Based on Morphological Metrics to Classify Neurons in Selective Populations
Published on: February 15, 2017
Related Concept Videos
Neural Circuits
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
The Role of Ion Channels in Neuronal Computation
Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential....
Neuronal Communication
Neuron Structure
Structure and Function of Neurons
The neuronal cell body—the soma— houses the nucleus and organelles vital to...
Neuron Structure
Neurons as Communicators of the Brain
Cell Body
The cell body, also known...