Percutaneous Endoscopic Gastrostomy Feeding in Children with Cerebral Palsy
Hasret Ayyildiz Civan1, Gonca Bektas2, Ali Evrim Dogan3
1Department of Pediatric Gastroenterology, Hepatology and Nutrition, Bakırköy Dr. Sadi Konuk Research and Training Hospital, University of Health Sciences, Istanbul, Turkey.
Insights
Percutaneous endoscopic gastrostomy (PEG) effectively improves malnutrition and reduces vomiting in pediatric cerebral palsy (CP) patients. This safe and cost-effective intervention enhances nutritional status and tolerability in this vulnerable population.
Area of Science:
- Pediatric Gastroenterology
- Clinical Nutrition
- Neurology
Background:
- Congenital cerebral palsy (CP) affects 0.15-0.4% of children globally.
- Gastrointestinal complications in CP hinder normal eating and lead to malnutrition.
- Effective nutritional support is crucial for managing pediatric CP patients.
Purpose of the Study:
- To evaluate the tolerability and benefits of percutaneous endoscopic gastrostomy (PEG) in pediatric CP patients with malnutrition.
- To assess the impact of PEG on nutritional status and gastrointestinal symptoms.
Main Methods:
- A single-center observational study involving 41 pediatric CP patients with malnutrition.
- Retrospective analysis of patient data, including anthropometric measurements and blood parameters (vitamin D3, folate, iron, zinc, B12, hemoglobin).
- Data collected at baseline and at 3 and 6 months post-PEG insertion, with standard polymeric enteral supplementation.
Main Results:
- Significant improvements in height, weight, and triceps skinfold thickness were observed at 3 and 6 months post-PEG (p < 0.05).
- A significant decrease in the number of patients with low hemoglobin levels was noted (p = 0.022).
- Vomiting frequency significantly reduced after PEG insertion at 3 and 6 months (p = 0.004).
Conclusions:
- Percutaneous endoscopic gastrostomy (PEG) is a safe and well-tolerated intervention for pediatric CP patients with malnutrition.
- PEG significantly improves nutritional status and reduces gastrointestinal complications like vomiting.
- PEG represents a beneficial and cost-effective treatment option for improving the quality of life in pediatric CP patients.
Aim:
The prevalence of congenital cerebral palsy (CP) worldwide ranges from 0.15 to 0.4%. CP causes several gastrointestinal complications that inhibit normal eating behavior. This single-center observational study aimed to determine the tolerability and benefits of percutaneous endoscopic gastrostomy (PEG) in pediatric CP patients with malnutrition.
Materials And Methods:
The study included 41 pediatric CP patients with malnutrition. All patient data were retrospectively obtained from Bakırköy Dr. Sadi Konuk Research and Training Hospital, Department of Pediatric Gastroenterology, Hepatology, and Nutrition, Istanbul, Turkey. In addition to baseline measurements of weight, height, triceps skinfold thickness, 1,25-hydroxyvitamin D3, folate, iron, zinc, vitamin B12, hemoglobin, and mean corpuscular volume, data analyzed included follow-up measurements recorded at 3 and 6 months of PEG (standard polymeric enteral supplementation as 1.0 kcal mL-1).
Results:
There was significant improvement in both height, weight, and triceps skinfold thickness in all patients at 3 and 6 months of PEG (p < 0.05). In terms of blood parameters, there was not significant improvement, except that the number of patients with a low hemoglobin count significantly decreased at 3 and 6 months of (p = 0.022). Moreover, the number of patients with vomiting after PEG also significantly decreased at 3 and 6 months of (p = 0.004).
Conclusion:
PEG significantly improves malnutrition in pediatric CP patients and does not cause any major complications. Based on these findings, we think PEG is a beneficial and cost-effective intervention with a high rate of tolerability in pediatric CP patients with malnutrition.
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