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An Allergic Risk Factor Analysis of Extraordinary Daytime Only Urinary Frequency in Children

Ling Hou1, Zhou Zhang1, Yue Du1

  • 1Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, 110004, People's Republic of China.

Risk Management and Healthcare Policy
|July 1, 2021
PubMed

Insights

Allergic conditions like eczema and allergic rhinitis are key risk factors for extraordinary daytime only urinary frequency (EDOUF) in children. Antihistamine treatment effectively alleviates EDOUF symptoms.

Area of Science:

  • Pediatrics
  • Allergology
  • Urology

Background:

  • Extraordinary daytime only urinary frequency (EDOUF) affects children, necessitating investigation into its underlying causes.
  • Allergic conditions are increasingly recognized as potential contributors to various pediatric health issues.

Purpose of the Study:

  • To identify significant risk factors associated with EDOUF in pediatric populations.
  • To evaluate the clinical efficacy of antihistamine treatment for EDOUF.

Main Methods:

  • Retrospective analysis of medical records for 266 children diagnosed with EDOUF.
  • Correlation and binary logistic regression analyses were employed to assess risk factors.
  • Evaluation of treatment outcomes following oral antihistamine (desloratadine) administration.

Main Results:

  • Eczema (OR=8.393), allergic rhinitis/cough (OR=4.459), pruritus (OR=3.879), and elevated total serum IgE (OR=7.927) were identified as significant risk factors for EDOUF.
  • The study included 266 children (127 boys, 139 girls) with an average age of 5.60 ± 2.04 years.
  • Oral desloratadine demonstrated an 89.1% efficacy rate in alleviating EDOUF symptoms.

Conclusions:

  • Pediatric EDOUF is strongly linked to systemic or local allergic conditions, including eczema, allergic rhinitis, allergic cough, and pruritus.
  • Elevated total serum IgE levels are also a significant risk factor for EDOUF.
  • Antihistamine therapy, specifically oral desloratadine, proves effective in managing EDOUF symptoms in children.
Abstract

Keywords:
allergychildrenextraordinary daytime only urinary frequencyloratadinerisk factor

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