Related Experiment Video
Updated: Oct 31, 2025
10:52
Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis
Published on: December 17, 2010
14.8K
Case Report: Severe Hypocalcemic Episodes Due to Autoimmune Enteropathy
Inbal Halabi1,2, Marie Noufi Barohom1,2,3, Sarit Peleg4
1Pediatric Endocrine Institute, Ha'Emek Medical Center, Afula, Israel.
Frontiers in Endocrinology
|July 1, 2021
Summary
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) can cause autoimmune enteropathy (AIE) due to gut endocrine cell loss. Recognizing this rare GI manifestation is crucial for timely diagnosis and management of APECED patients.
Area of Science:
- Endocrinology
- Gastroenterology
- Genetics
Background:
- Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is a rare genetic disorder with endocrine and non-endocrine features.
- Gastrointestinal (GI) issues affect 25% of APECED patients, often presenting as autoimmune enteropathy (AIE) due to gut endocrine cell destruction.
- Pediatricians' limited awareness of AIE in APECED can delay diagnosis and treatment.
