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Updated: Oct 31, 2025

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
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A minimal hybridization chain reaction (HCR) system using peptide nucleic acids

Ki Tae Kim1, Simona Angerani1, Nicolas Winssinger1

  • 1University of Geneva Switzerland nicolas.winssinger@unige.ch.

Chemical Science
|July 1, 2021
PubMed
Summary

This study introduces a minimal hairpin cascade reaction (HCR) system using peptide nucleic acids (PNAs). This PNA-based HCR enables rapid DNA amplification for sensitive cancer biomarker detection on live cells.

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