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Introduction to molecular replacement: a time perspective
1Department of Chemistry, University of York, Heslington, York YO10 5DD, United Kingdom.
Abstract:
This article provides an introduction to the crystal phasing technique known as molecular replacement. The available software is reviewed, and the prospects for future developments are considered. Several examples are described in detail to illustrate potential problems. A brief account of past progress is included. The basic crystallographic equations underlying the procedures are given in an appendix.
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