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Auditory brainstem response with click and CE-Chirp® Level Specific stimuli in hearing infants
Diego da Silva Ormundo1, Doris Ruthy Lewis1
1Faculty of Health and Human Sciences, Pontifical Catholic University of São Paulo, São Paulo, Brazil.
Summary
The CE-Chirp® Level Specific (LS) stimulus shows advantages over traditional Click stimuli for assessing auditory brainstem responses (ABR) in infants. It elicits higher wave V amplitudes and improved waveform morphology, aiding in the diagnosis of auditory pathway alterations.
Area of Science:
- Auditory Neuroscience
- Neurophysiology
- Audiology
Background:
- Auditory Brainstem Response (ABR) testing assesses neural integrity for diagnosing retrocochlear alterations.
- Click stimuli are the standard for ABR, but CE-Chirp® Level Specific (LS) was developed to enhance neural response triggering.
Purpose of the Study:
- To compare neural responses evoked by CE-Chirp® LS and Click stimuli in hearing infants at 70 dB nHL.
- To analyze the advantages of using CE-Chirp® LS stimulus in auditory assessments.
Main Methods:
- Eighteen normal-hearing infants underwent ABR testing using the Eclipse EP25 ABR System.
- Both Click and CE-Chirp® LS stimuli were presented at 70 dB nHL via insert earphones.
- Measurements included wave latencies, interpeak intervals, interaural differences, and wave V amplitude.
Main Results:
- CE-Chirp® LS evoked significantly higher wave V amplitude compared to Click stimuli (p < 0.001).
- Statistically significant differences were observed in absolute latencies of waves I and III, and interpeak intervals I-III and I-V.
- Wave V absolute latency and interaural differences showed no significant differences between the stimuli.
Conclusions:
- CE-Chirp® LS stimulus is suitable for analyzing neural synchrony in infants at 70 dB nHL, offering improved waveform morphology and higher wave V amplitudes.
- Further research is recommended to evaluate CE-Chirp® LS in infants with neurological disabilities and varying hearing statuses.

