Related Experiment Video
Updated: Oct 31, 2025

07:10
Split Hybridization Probe Utilizing a DNA Fluorescent Light-up Aptamer as a Signal Reporter for Sequence-Specific Nucleic Acid Analysis
Published on: July 8, 2025
663
Dual role of silver in a fluorogenic N-squaraine probe based on Ag(I)-π interactions
Manel Vega1, Salvador Blasco2, Enrique García-España2
1Department of Chemistry, Universitat de les Illes Balears, Ctra. Valldemossa km 7.5, 07122, Palma, Spain. antoni.costa@uib.es.
Dalton Transactions (Cambridge, England : 2003)
|July 1, 2021
Abstract:
In the presence of Ag(i), the monoanion of cyano-N-squaraine (I) generates an intense fluorescence turn-on response. Experimental evidence and DFT calculations reveal a sequence of deprotonation-coordination events in which the Ag(i) ions play a dual role as a Lewis acid and coordinating metal. The observed effect is highly selective for Ag(i) compared to other metals.

