Management of a Mycotic Aneurysm in a Patient with COVID-19: A Case Report

Muzammil H Syed1, Mark Wheatcroft1,2, Danny Marcuzzi3

  • 1Division of Vascular Surgery, St. Michael's Hospital, Toronto, ON M5B 1W8, Canada.

Insights

This case study details managing a patient with a Klebsiella pneumoniae mycotic abdominal aortic aneurysm and COVID-19. Rifampin-coated endovascular stent grafts offer a viable bridge to surgery for high-risk patients.

Area of Science:

  • Vascular Surgery
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Mycotic abdominal aortic aneurysms (MAAAs) pose significant surgical challenges, particularly when co-infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
  • Managing MAAAs in critically ill patients requires innovative approaches to mitigate high operative risks.

Observation:

  • A 69-year-old male with a rapidly expanding infra-renal MAAA due to Klebsiella pneumoniae developed severe SARS-CoV-2 infection requiring intubation.
  • The patient's MAAA increased from 2.5 cm to 3.9 cm during his COVID-19 illness.

Findings:

  • Emergency endovascular repair was successfully performed using a rifampin-coated stent graft.
  • The patient experienced no major complications, neurological deficits, or vascular compromise post-procedure.
  • Follow-up imaging at 6 weeks and 180 days confirmed a patent stent graft with a reduced aneurysm sac size and no signs of infection or endoleak.

Implications:

  • Rifampin-coated endovascular stent grafts can serve as a crucial bridge to definitive treatment for high-risk patients with MAAAs.
  • This approach demonstrates a potentially life-saving strategy in complex cases involving concurrent severe infections.
  • Further research into endovascular techniques for infected aortic aneurysms is warranted.

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