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Published on: September 25, 2009
Management of a Mycotic Aneurysm in a Patient with COVID-19: A Case Report
Muzammil H Syed1, Mark Wheatcroft1,2, Danny Marcuzzi3
1Division of Vascular Surgery, St. Michael's Hospital, Toronto, ON M5B 1W8, Canada.
Abstract:
The aim of this paper is to share our experience in managing a patient with Klebsiella pneumoniae mycotic abdominal aortic aneurysm who was also infected with COVID-19. A 69-year-old male was transferred to our hospital for the management of an infra-renal mycotic abdominal aortic aneurysm. During his hospital course, the patient contracted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). He was intubated due to respiratory distress. Over a short period, his mycotic aneurysm increased in size from 2.5 cm to 3.9 cm. An emergency repair of his expanding aneurysm was achieved using our previously described protocol of coating endovascular stents with rifampin. The patient was managed with a rifampin-coated endovascular stent graft without any major complications. Postoperatively, the patient did not demonstrate any neurological deficits nor any vascular compromise. He remained afebrile during his postoperative course and was extubated sometime thereafter. He was then transferred to the ward for additional monitoring prior to his discharge to a rehab hospital while being on long-term antibiotics. During his hospital stay, he was monitored with serial ultrasounds to ensure the absence of abscess formation, aortic aneurysm growth or graft endoleak. At 6 weeks after stent graft placement, he underwent a CT scan, which showed a patent stent graft, with a residual sac size of 2.5 cm without any evidence of abscess or endoleak. Over a follow-up period of 180 days, the patient remained asymptomatic while remaining on long-term antibiotics. Thus, in patients whose surgical risk is prohibitive, endovascular stent grafts can be used as a bridge to definitive surgical management.
Insights
This case study details managing a patient with a Klebsiella pneumoniae mycotic abdominal aortic aneurysm and COVID-19. Rifampin-coated endovascular stent grafts offer a viable bridge to surgery for high-risk patients.
Area of Science:
- Vascular Surgery
- Infectious Diseases
- Critical Care Medicine
Background:
- Mycotic abdominal aortic aneurysms (MAAAs) pose significant surgical challenges, particularly when co-infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
- Managing MAAAs in critically ill patients requires innovative approaches to mitigate high operative risks.
Observation:
- A 69-year-old male with a rapidly expanding infra-renal MAAA due to Klebsiella pneumoniae developed severe SARS-CoV-2 infection requiring intubation.
- The patient's MAAA increased from 2.5 cm to 3.9 cm during his COVID-19 illness.
Findings:
- Emergency endovascular repair was successfully performed using a rifampin-coated stent graft.
- The patient experienced no major complications, neurological deficits, or vascular compromise post-procedure.
- Follow-up imaging at 6 weeks and 180 days confirmed a patent stent graft with a reduced aneurysm sac size and no signs of infection or endoleak.
Implications:
- Rifampin-coated endovascular stent grafts can serve as a crucial bridge to definitive treatment for high-risk patients with MAAAs.
- This approach demonstrates a potentially life-saving strategy in complex cases involving concurrent severe infections.
- Further research into endovascular techniques for infected aortic aneurysms is warranted.
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