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Updated: Oct 30, 2025

Quantification of Hypopigmentation Activity In Vitro
Published on: March 6, 2019
Anti-Pigmentary Natural Compounds and Their Mode of Action
Kyuri Kim1, YoonJung Huh1, Kyung-Min Lim1
1College of Pharmacy, Ewha Womans University, Seodaemungu, Seoul 03760, Korea.
Abstract:
Hyper-activated melanocytes are the major cause of skin hyper-pigmentary disorders, such as freckles and melasma. Increasing efforts have been made to search for materials with depigmenting activity to develop functional cosmetics. As a result, numerous materials have been reported to have depigmenting activity but some of them are known to cause unwanted side effects. Consequently, anti-pigmentary natural compounds without concern of toxicity are in great demand. Virtually all sorts of natural sources have been investigated to find anti-pigmentary natural compounds. This review summarizes recently reported anti-pigmentary natural compounds and their mode of action from the ocean, plants, and bacteria.
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