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Multidrug Resistence Prevalence in COVID Area.

Caterina Aurilio1, Pasquale Sansone1, Antonella Paladini2

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This review examines antibiotic resistance and bacterial co-infections in COVID-19 patients. It highlights how multidrug-resistant bacteria increase morbidity and mortality in critically ill patients with SARS-CoV-2 infection.

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Area of Science:

  • Infectious Diseases
  • Microbiology
  • Critical Care Medicine

Background:

  • Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, frequently leads to severe acute respiratory syndrome.
  • The rapid global spread resulted in a pandemic, with over 100 million cases by early 2021.
  • Bacterial co-infections are common in hospitalized COVID-19 patients, particularly in intensive care units.

Purpose of the Study:

  • To review recent literature on antibiotic resistance and viruses.
  • To identify risk factors associated with COVID-19.
  • To assess multidrug resistance in patients hospitalized with COVID-19.

Main Methods:

  • Systematic review of recent articles.
  • Analysis of studies focusing on antibiotic resistance in viral infections.
  • Examination of data on bacterial co-infections in COVID-19 patients.

Main Results:

  • Antimicrobial drug use is frequent for managing bacterial co-infections in COVID-19 patients.
  • Critically ill patients on mechanical ventilation are susceptible to hospital-acquired co-infections.
  • Multidrug-resistant bacteria contribute significantly to increased morbidity and mortality.

Conclusions:

  • Bacterial co-infections and antibiotic resistance are critical factors influencing outcomes in COVID-19.
  • Understanding these factors is essential for managing critically ill patients.
  • Further research is needed to predict and mitigate risks associated with co-infections in COVID-19.